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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C14orf135
All Species:
7.88
Human Site:
S345
Identified Species:
21.67
UniProt:
Q63HM2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q63HM2
NP_071940.4
1172
132702
S345
T
K
S
K
D
L
P
S
G
P
E
K
H
F
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095482
1171
132403
S345
T
K
S
K
N
L
P
S
G
P
E
K
H
F
S
Dog
Lupus familis
XP_537464
1179
132983
S352
T
K
S
K
A
S
P
S
G
S
E
K
Q
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVY5
1174
131224
V345
Y
G
V
T
R
H
R
V
G
S
S
H
E
A
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517126
1186
130775
A345
R
I
G
T
R
Q
V
A
A
P
Q
S
A
P
L
Chicken
Gallus gallus
XP_421424
1183
133584
A345
H
T
M
S
S
R
L
A
S
S
K
S
K
A
M
Frog
Xenopus laevis
Q5HZQ9
1184
134013
P345
H
H
L
K
R
L
S
P
F
M
K
S
T
S
P
Zebra Danio
Brachydanio rerio
A2RUW7
1225
134598
L351
G
V
S
P
T
L
G
L
G
W
W
G
L
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785575
1251
139735
K343
A
F
I
K
Q
C
V
K
K
P
T
N
H
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96
84.9
N.A.
76.4
N.A.
N.A.
66.3
68.9
61.1
49.9
N.A.
N.A.
N.A.
N.A.
40.1
Protein Similarity:
100
N.A.
97.8
91.3
N.A.
85.4
N.A.
N.A.
78.1
81.8
77.6
67
N.A.
N.A.
N.A.
N.A.
59.7
P-Site Identity:
100
N.A.
93.3
66.6
N.A.
6.6
N.A.
N.A.
6.6
0
13.3
20
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
100
73.3
N.A.
6.6
N.A.
N.A.
20
13.3
20
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
23
12
0
0
0
12
23
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
34
0
12
0
0
% E
% Phe:
0
12
0
0
0
0
0
0
12
0
0
0
0
34
0
% F
% Gly:
12
12
12
0
0
0
12
0
56
0
0
12
0
0
0
% G
% His:
23
12
0
0
0
12
0
0
0
0
0
12
34
0
0
% H
% Ile:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
34
0
56
0
0
0
12
12
0
23
34
12
0
0
% K
% Leu:
0
0
12
0
0
45
12
12
0
0
0
0
12
0
23
% L
% Met:
0
0
12
0
0
0
0
0
0
12
0
0
0
0
12
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
12
0
0
34
12
0
45
0
0
0
23
23
% P
% Gln:
0
0
0
0
12
12
0
0
0
0
12
0
12
0
0
% Q
% Arg:
12
0
0
0
34
12
12
0
0
0
0
0
0
0
12
% R
% Ser:
0
0
45
12
12
12
12
34
12
34
12
34
0
23
23
% S
% Thr:
34
12
0
23
12
0
0
0
0
0
12
0
12
0
12
% T
% Val:
0
12
12
0
0
0
23
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _